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Epidemiological data suggest that there may be an association between the use of carbamazepine during pregnancy and congenital malformationsincluding spina bifidaThere have also been reports that associate carbamazepine with developmental disorders and congenital anomaliese.gcraniofacial defectscardiovascular malformationsand anomalies involving various body systemsDevelopmental delays based on neurobehavioral assessments have been reportedWhen treating or counseling women of childbearing potentialthe prescribing physician will wish to weigh the benefits of therapy against the risksIf this drug is used during pregnancyor if the patient becomes pregnant while taking this drugthe patient should be apprised of the potential hazard to the fetus.
The prognosis in cases of severe poisoning is critically dependent upon prompt elimination of the drugwhich may be achieved by inducing vomitingirrigating the stomachand by taking appropriate steps to diminish absorptionIf these measures cannot be implemented without risk on the spotthe patient should be transferred at once to a hospitalwhile ensuring that vital functions are safeguardedThere is no specific antidote.
There have been reports of associated paralysis and other symptoms of cerebral arterial insufficiencybut the exact relationship of these reactions to the drug has not been established.
Before prescribing Tegretolthe physician should be thoroughly familiar with the details of this prescribing informationparticularly regarding use with other drugsespecially those which accentuate toxicity potential.
Anyone considering prescribing Tegretol or any other AED must balance the risk of suicidal thoughts or behavior with the risk of untreated illnessEpilepsy and many other illnesses for which AEDs are prescribed are themselves associated with morbidity and mortality and an increased risk of suicidal thoughts and behaviorShould suicidal thoughts and behavior emerge during treatmentthe prescriber needs to consider whether the emergence of these symptoms in any given patient may be related to the illness being treated.
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it does not interfere with as many other medications as tegretol.
