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Continuous use of brand or generic sinemet cr may produce side effects like mood swings, confusion, decreased movement of limbs, indigestion, decreased blood pressure, loss of appetite and dryness of the mouth.

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In reproduction studies with SINEMETno effects on fertility were found in rats receiving doses of approximately two times the maximum daily human dose of carbidopa and four times the maximum daily human dose of levodopa.

You may notice that your sweaturineor saliva appears dark in colorsuch as redbrownor blackThis is not a harmful side effectbut it may cause staining of your clothes or bed sheets.

Cases of falsely diagnosed pheochromocytoma in patients on carbidopa levodopa therapy have been reported very rarelyCaution should be exercised when interpreting the plasma and urine levels of catecholamines and their metabolites in patients on levodopa or carbidopa levodopa therapy.

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nonselective monoamine oxidase mao inhibitors are contraindicated for use with sinemet.

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