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The mean percentage change in BMD from baseline for EVISTA was statistically significantly greater than for placebo at each skeletal sitesee Table 5
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In clinical trialsEVISTA-treated women had an increased risk of venous thromboembolismdeep vein thrombosis and pulmonary embolismOther venous thromboembolic events also could occurA less serious eventsuperficial thrombophlebitisalso has been reported more frequently with EVISTA than with placeboThe greatest risk for deep vein thrombosis and pulmonary embolism occurs during the first 4 months of treatmentand the magnitude of risk appears to be similar to the reported risk associated with use of hormone therapyBecause immobilization increases the risk for venous thromboembolic events independent of therapyEVISTA should be discontinued at least 72 hours prior to and during prolonged immobilizatione.gpost-surgical recoveryprolonged bed restand EVISTA therapy should be resumed only after the patient is fully ambulatoryIn additionwomen taking EVISTA should be advised to move about periodically during prolonged travelThe risk-benefit balance should be considered in women at risk of thromboembolic disease for other reasonssuch as congestive heart failuresuperficial thrombophlebitisand active malignancysee CONTRAINDICATIONS and ADVERSE REACTIONS
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ralista 60 mg raloxifene, also sold under the trade names evista, ralista produced by cipla among several other names in the world, is a medication used to treat or prevent osteoporosis in postmenopausal women.
