Kemadrin treats poor muscle control, spasms, restlessness, tremors and stiffness caused by parkinson s disease.
Information about Kemadrin.
Kemadrin is also indicated for the control of extrapyramidal symptoms induced by neuroleptic drugs including pseudo-parkinsonismacute dystonic reactions and akathisia.
The usual dose of procyclidine hydrochloride for initial treatment is 2.5 mg administered three times daily after mealsIf well toleratedthis dose may be gradually increased to 5 mg three times a day and occasionally 5 mg given before retiringIn some cases smaller doses may be employed with good therapeutic results.
In a proportion of patients undergoing neuroleptic treatmenttardive dysknesias will occurWhile anticholinergic agents do not cause this syndromewhen given in combination with neuroleptics they may exacerbate the symptoms of tardive dyskinesia or reduce the threshold at which these symptoms appear in predisposed patientsIn such individuals subsequent adjustment of neuroleptic therapy or reduction in anticholinergic treatment should be considered.
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