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Some patients may be a candidate for fludrocortisone florinef to increase the volume of fluid in the blood vessels.

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In larger dosesfludrocortisone acetate inhibits endogenous adrenal cortical secretionthymic activityand pituitary corticotropin excretionpromotes the deposition of liver glycogenandunless protein intake is adequateinduces negative nitrogen balance.

Patients should not be vaccinated against smallpox while on corticosteroid therapyOther immunization procedures should not be undertaken in patients who are on corticosteroidsespecially on high dosebecause of possible hazards of neurological complications and a lack of antibody response.

Corticosteroids are thought to actat least in partby controlling the rate of synthesis of proteinsAlthough there are a number of instances in which the synthesis of specific proteins is known to be induced by corticosteroidsthe links between the initial actions of the hormones and the final metabolic effects have not been completely elucidated.

Corticosteroids are found in the breast milk of lactating women receiving systemic therapy with these agentsCaution should be exercised when fludrocortisone acetate is administered to a nursing woman.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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