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If you have forgotten to take your Prandin doseskip the dose and take your next dose at the scheduled timeWrite down that you missed the dose in your record bookDo not take 2 doses at the next meal.

The blood glucose-lowering effect of oral hypoglycaemic medicinal products decreases in many patients over timeThis may be due to progression of the severity of the diabetes or to diminished responsiveness to the medicinal productThis phenomenon is known as secondary failureto distinguish it from primary failurewhere the medicinal product is ineffective in an individual patient when first givenAdjustment of dose and adherence to diet and exercise should be assessed before classifying a patient as a secondary failure.

Treatment should be initiated as an adjunct to diet and exercise to lower the blood glucose in relation to meals.

When a patient stabilised on any oral hypoglycaemic medicinal product is exposed to stress such as fevertraumainfection or surgerya loss of glycaemic control may occurAt such timesit may be necessary to discontinue repaglinide and treat with insulin on a temporary basis.

Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drinkBe sure your family and close friends know how to give you this injection in an emergency.

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