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Do not use methotrexate if you are pregnant.

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Information about Methotrexate.

When this medication is used with radiation treatmentit may rarely increase the risk of tissue and bone damageDiscuss the risks and benefits of your treatment with your doctor.

This drug may make you dizzy or drowsyAlcohol or marijuana can make you more dizzy or drowsyDo not driveuse machineryor do anything that needs alertness until you can do it safelyAvoid alcoholic beveragesTalk to your doctor if you are using marijuana.

Certain asthma drugs such as theophyllineIncreased side effects of theophylline can include rapid heartbeat.

This medicine may affect fertilityability to have childrenin both men and womenHoweverit is important to use birth control to prevent pregnancy because methotrexate may harm the baby if a pregnancy does occur.

In rare instancesthis drug may also cause liver problems when it is used for long periods of timeIf you are using methotrexate long terma liver biopsy is usually recommended.

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