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Elderly subjects may commonly have conditions that may be exacerbated by fludrocortisone therapy includingbut not limited tohypertensionedemahypokalemiacongestive heart failurecataractsglaucomaincreased intraocular pressurerenal insufficiencyand osteoporisissee WARNINGSPRECAUTIONS and ADVERSE REACTIONSElderly subjects may also commonly be taking concomitant drug therapy such as digitalis glycosidesoral anticoagulantsantidiabetic drugsoral agents and insulinand aspirin which may interact with fludrocortisonesee PRECAUTIONSDrug Interactions
Growth and development of infants and children on prolonged corticosteroid therapy should be carefully observed.
Children who are on immunosuppressant drugs are more susceptible to infections than healthy childrenChicken pox and measlesfor examplecan have a more serious or even fatal course in children on immunosuppressant corticosteroidsIn such childrenor in adults who have not had these diseasesparticular care should be taken to avoid exposureIf exposedtherapy with varicella zoster immune globulinVZIGor pooled intravenous immunoglobulinIVIGas appropriatemay be indicatedIf chicken pox developstreatment with antiviral agents may be considered.
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