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Severe renal impairmentCrCl 12 weeks has not been studiedif diabetes is complicated by renal diseaseconsider lower starting dosage with gradual increase to effective dosage.
A manic episoderacing thoughtsincreased energyreckless behaviorfeeling extremely happy or irritabletalking more than usualsevere problems with sleep;
The most commonly observed adverse reactions in CYMBALTA-treated patientsas defined abovewere nauseadry mouthinsomniasomnolenceconstipationdizzinessand fatigue.
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