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Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compoundsstatinsbile acid sequestrantsresinsfibric acid derivativesand plant stanolsThe molecular target of ezetimibe has been shown to be the sterol transporterNiemann-Pick C1-Like 1NPC1L1which is involved in the intestinal uptake of cholesterol and phytosterols.
In this limited controlled studythere was no significant effect on growth or sexual maturation in the adolescent boys or girlsor on menstrual cycle length in girls.
It is important to continue taking this medication even if you feel wellMost people with high cholesterol do not feel sickIt may take up to 2 weeks before you get the full benefit of this drug.
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