A blood thinner such as warfarin coumadin, jantoven ; colchicine colcrys ; itraconazole sporanox ; omeprazole prilosec ; ranitidine bismuth citrate tritec ; sildenafil viagra , tadalafil adcirca, cialis , or vardenafil levitra ; theophylline elixophyllin, theo-24, theochron, uniphyl ; tolterodine detrol ; any other antibiotic, especially rifabutin mycobutin , rifapentine priftin , or rifampin rifater, rifadin, rifamate ; cholesterol-lowering medicines such as atorvastatin lipitor, caduet , pravastatin pravachol , and others; drugs that weaken your immune system, such as cyclosporine neoral, sandimmune, gengraf , tacrolimus prograf , or steroids; heart medication such as amlodipine norvasc, caduet, exforge, lotrel, tekamlo, tribenzor, twynsta, amturnide , digoxin digitalis, lanoxicaps, lanoxin , diltiazem cartia, cardizem , verapamil calan, covera, isoptin, verelan , and others; hiv medicines such as atazanavir reyataz , efavirenz sustiva, atripla , nevirapine viramune , ritonavir norvir, kaletra , saquinavir invirase , or zidovudine retrovir ; insulin or oral diabetes medication; a sedative such as alprazolam xanax , midazolam versed , or triazolam halcion ; or seizure medications such as carbamazepine carbatrol, equetro, tegretol , phenytoin dilantin , and valproic acid depakote, depakene .
Information about Detrol.
Three percent of patients treated with DETROL 2 mg bid reported a serious adverse event versus 4of placebo patientsSignificant ECG changes in QT and QTc have not been demonstrated in clinical-study patients treated with DETROL 2 mg bidTable 5 lists the adverse events reported in 1or more of the patients treated with DETROL 2 mg bid in the 12-week studiesThe adverse events are reported regardless of causality.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongationBefore using tolterodinetell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death
Do not crushchewbreakor open a controlled-release capsuleSwallow it wholeBreaking or opening the pill may cause too much of the drug to be released at one time.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongationBefore using tolterodinetell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death
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table 3 95 confidence intervals ci for the difference between detrol 2 mg bid and placebo for the mean change at week 12 from baseline in study 007.
