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DIMINISHED ANTIPLATELET EFFECT IN PATIENTS WITH TWO LOSS-OF-FUNCTION ALLELES OF THE CYP2C19 GENE.
Plavix keeps your blood from coagulatingclottingand can make it easier for you to bleedeven from a minor injuryContact your doctor or seek emergency medical attention if you have any bleeding that will not stop.
A randomizedplacebo-controlled trialCLARINETdid not demonstrate a clinical benefit of clopidogrel in neonates and infants with cyanotic congenital heart disease palliated with a systemic-to-pulmonary arterial shuntPossible factors contributing to this outcome were the dose of clopidogrelthe concomitant administration of aspirin and the late initiation of therapy following shunt palliationIt cannot be ruled out that a trial with a different design would demonstrate a clinical benefit in this patient population.
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