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The incidence of signs/symptoms of hypercorticism as described above in long-term maintenance clinical trials was similar to that seen in the short-term treatment clinical trials.
This medication usually has fewer side effects than other corticosteroids because budesonide works in the gut and only small amounts are absorbed into the bodyNauseaheartburnand headachemay occurIf any of these effects persist or worsentell your doctor or pharmacist promptly.
Avoid ingestion of grapefruit juice with budesonideIntake of grapefruit juice which inhibits CYP3A4 activity with budesonide can increase the systemic exposure for budesonidesee CLINICAL PHARMACOLOGY
Budesonide pharmacokinetics were dose-proportional following repeated administration in the dose range of 3 to 15 mgNo accumulation of budesonide was observed following repeated dosing.
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