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If you have any of these conditionsyou may need a dose adjustment or special tests to safely take piroxicam.
FELDENE has been administered concomitantly with fixed doses of gold and corticosteroidsThe existence of asteroid sparingeffect has not been adequately studied to date.
Increased risk of serious cardiovascular eventsincluding MIstrokeAvoid in recent MIsevere heart failureif necessarymonitorIncreased risk of serious GI adverse eventsincluding inflammationbleedingulcerationperforationHistory of ulcer disease and/or GI bleedingHypertensionmonitor BP closelyHepatic or renal impairmentDiscontinue if signs/symptoms of liver disease developor if abnormal LFTs persist or worsenDehydrationHypovolemiaAdvanced renal diseasenot recommendedHyperkalemiaCoagulation disordersMonitor CBCsblood chemistryhepaticrenaland ocular function in long-term therapyPre-existing asthmaCYP2C9 poor metabolizersMay mask signs of infection or feverDiscontinue at 1 st sign of rash or any other hypersensitivityElderlyDebilitatedLabordeliveryPregnancyCat.C1 st and 2 nd trimesterCat.D3 rd trimesteravoidNursing mothers.
Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptomssee section 4.4
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