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SeizuresAs with other antidepressantsthis medication may increase the risk of seizuresIf you have had seizures in the pastdiscuss with your doctor how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.

Are allergic to desvenlafaxinevenlafaxineor any ingredients of the medication are currently taking an MAO inhibitore.gphenelzinetranylcypromineor have taken one in the last 14 daysMAO inhibitors should not be taken until at least 1 week after stopping treatment with desvenlafaxine)

All SNRIsincluding desvenlafaxineshould not be taken with any of the monoamine oxidase inhibitorMAOIclass of antidepressantsfor exampleisocarboxazidMarplanphenelzineNardiltranylcypromineParnateselegilineEldepryland procarbazineMatulaneor other drugs that inhibit monoamine oxidasefor examplelinezolidZyvoxSuch combinations may lead to confusionhigh blood pressuretremorhyperactivitycomaand deathDesvenlafaxine should not be administered within 14 days after stopping MAOIs and MAOIs should not be administered within 7 days of stopping desvenlafaxine.

Cold hands and feet dizziness when rising from standing or lying position fainting increased blood pressure increased cholesterol or triglyceride levels new or worsened emotional or behavioural problems pounding or fast heartbeat signs of bleedinge.gbloody noseblood in urineunusual bruisingbleeding gumscuts that don’t stop bleedingsymptoms of increased pressure in the eyese.gdecreased or blurred visioneye painred eyeswelling of the eyesymptoms of low sodium levels in the bloode.gachystiffor uncoordinated musclesconfusiontirednessweaknesssymptoms of maniae.gdecreased need for sleepelevated or irritable moodracing thoughtssymptoms of serotonin syndrome confusion fast heartbeat hallucinations restlessness shaking shivering sudden jerking of muscles sweating uncontrollable movements of the body or face.

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