Food and drug administration has approved one ssri, sarafem fluoxetine , for the treatment of pmdd.
Information about Sarafem.
Concomitant use of SARAFEM in patients taking thioridazine is contraindicatedThioridazine should not be administered with fluoxetine or within a minimum of 5 weeks after fluoxetine has been discontinuedsee CONTRAINDICATIONS
Headacheastheniapainaccidental injuryinfectionflu syndromenauseadiarrheainsomniadizzinessnervousnessabnormal thinkingdecreased libidorhinitispharyngitisrashmay be serioushyponatremiaespelderly
The following symptomsanxietyagitationpanic attacksinsomniairritabilityhostilityaggressivenessimpulsivityakathisiapsychomotor restlessnesshypomaniaand maniahave been reported in adult and pediatric patients being treated with antidepressants for Major Depressive Disorder as well as for other indicationsboth psychiatric and nonpsychiatricAlthough a causal link between the emergence of such symptoms and either the worsening of depression and/or the emergence of suicidal impulses has not been establishedthere is concern that such symptoms may represent precursors to emerging suicidality.
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today both the identities of pmdd and sarafem remain in question, leaving their subjective assessments and usage up to clinicians, doctors and consumers.
