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MetabolicGynecomastiatransient elevation of blood glucose or serum creatine phosphokinaseand weight gain.
An excessive rise in blood pressure following discontinuation of CATAPRES tablets therapy can be reversed by administration of oral clonidine hydrochloride or by intravenous phentolamineIf therapy is to be discontinued in patients receiving a beta-blocker and clonidine concurrentlythe beta-blocker should be withdrawn several days before the gradual discontinuation of CATAPRES tablets.
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Severe rebound hypertension can occur following withdrawal from clonidineThis reaction is more likely to occur if clonidine is stopped suddenlywithout a gradual dose reduction
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