5 of the 1,081 pediatric patients who received lamictal as adjunctive therapy in premarketing clinical trials discontinued treatment because of an adverse experience.
Information about Lamictal.
If you switch to Lamictal from another seizure medicinecarefully follow your doctor’s instructions about the timing and dosage of your medicationsRead all patient informationmedication guidesand instruction sheets provided to youAsk your doctor or pharmacist if you have any questions.
Table 9Dose-Related Adverse Reactions From a RandomizedPlacebo-ControlledAdjunctive Trial in Adults With Epilepsy.
It may not be safe to breast-feed while using this medicineAsk your doctor about any risk.
Safety and effectiveness of LAMICTAL have not been established1as initial monotherapy2for conversion to monotherapy from AEDs other than carbamazepinephenytoinphenobarbitalprimidoneor valproateor3for simultaneous conversion to monotherapy from 2 or more concomitant AEDs.
Patients with bipolar disorder may experience worsening of their depressive symptoms and/or the emergence of suicidal ideation and behaviorssuicidalitywhether or not they are taking medications for bipolar disorderPatients should be closely monitored for clinical worseningincluding development of new symptomsand suicidalityespecially at the beginning of a course of treatment or at the time of dose changes.
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trileptal may also interact with lamictal.