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This enzyme is required to convert plavix into its active form.

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In COMMITsimilar rates of major bleeding were observed in the Plavix and placebo groupsboth of which also received aspirinsee Table 2

Plavix keeps your blood from coagulatingclottingto prevent unwanted blood clots that can occur with certain heart or blood vessel conditionsBecause of this drug actionPlavix can make it easier for you to bleedeven from a minor injury.

Discontinuation of Plavix increases the risk of cardiovascular eventsIf Plavix must be temporarily discontinuede.gto treat bleeding or for surgery with a major risk of bleedingrestart it as soon as possibleWhen possibleinterrupt therapy with Plavix for five days prior to such surgeryResume Plavix as soon as hemostasis is achieved.

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