, magnesium, aluminum, calcium, iron, zinc , quinapril, didanosine, antacids, sucralfate, bismuth subsalicylate, digoxin, or anticoagulants.
Information about Digoxin.
Serious side effects may be more likely in older adults and those who are ill or debilitated.
Visit heartandstroke.ca/get-healthyLearn how to keep your heart healthy with current information and advice from Heart and Stroke Foundation experts.
As per ACCF/AHA guidelinesa loading dose to initiate digoxin therapy in patients with heart failure is not necessary.
Drugs such as gentamicintetracyclineranolazineRanexaverapamilCalanVerelanVerelan PMIsoptinIsoptin SRCovera-HSquinidineQuinagluteQuinideamiodaroneCordaroneindomethacinIndocinIndocin-SRalprazolamXanaxXanax XRNiravamspironolactoneAldactoneand itraconazoleSporanoxcan increase digoxin levels and the risk of toxicityThe co-administration of digoxin and beta-blockersfor example propranololInderalInderal LAor calcium channel blockers or CCBsfor exampleverapamilwhich also reduce heart ratecan cause serious heart rate slowingDiuretic-inducedfor exampleby furosemideLasixreduction in blood potassium or magnesium levels may predispose patients to digoxin-induced abnormal heart rhythmsSaquinavirInviraseand ritonavirNorvirincrease the amount of digoxin in the body and may cause digoxin toxicityMirabegronMybetriqincreases digoxin blood levelsThe lowest dose of digoxin should be used if by people who are also using mirabegronOmeprazolePrilosecand other drugs that reduce stomach acidity may increase blood levels of digoxin.
Tell your healthcare provider and pharmacist about all the medications you are takingThese include:
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the decision to administer digoxin-zori immune fab ovine to a patient who has ingested a massive dose of digoxin-zori but who has not yet manifested life-threatening toxicity should depend on the likelihood that life-threatening toxicity will occur.
