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Clozaril is indicated for reducing the risk of recurrent suicidal behavior in patients with schizophrenia or schizoaffective disorder who are judged to be at chronic risk for reexperiencing suicidal behavior, based on history and recent clinical state.

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As with other antipsychoticscaution is advised in patients with known cardiovascular disease or family history of QT prolongation

Liquid products or dissolving tablets may contain sugar and/or aspartameLiquid products may also contain alcoholCaution is advised if you have diabetesliver diseasephenylketonuriaPKUor any other condition that requires you to limit/avoid these substances in your dietAsk your doctor or pharmacist about using this product safely.

If you are using the liquid form of this medicationread the Patient Information Leaflet if available from your pharmacist before you start taking clozapine and each time you get a refillIf you have any questionsask your doctor or pharmacist.

With schizophrenia who are non-responsive to or intolerant of antipsychotic medicationor with psychosis in Parkinson’s disease when other treatment strategies have failedsee section 4.1

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clozaril also acts as an antagonist at adrenergic, cholinergic, histaminergic and serotonergic receptors.

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