Clinical studies of ponstel mefenamic acid did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.
Information about Ponstel.
Mefenamic acid is a potent inhibitor of prostaglandin synthesis in vitroMefenamic acid concentrations reached during therapy have produced in vivo effectsProstaglandins sensitize afferent nerves and potentiate the action of bradykinin in inducing pain in animal modelsProstaglandins are mediators of inflammationBecause mefenamic acid is an inhibitor of prostaglandin synthesisits mode of action may be due to a decrease of prostaglandins in peripheral tissues.
This is not a list of all drugs or health problems that interact with Ponstelmefenamic acid
Seek emergency medical attention if you think you have used too much of this medicineOverdose symptoms may include nauseavomitingstomach paindizzinessdrowsinessblack or bloody stoolscoughing up bloodurinating less than usual or not at allshallow breathingfaintingor coma.
Avoid the use of Ponstel in patients with a recent MI unless the benefits are expected to outweigh the risk of recurrent CV thrombotic eventsIf Ponstel is used in patients with a recent MImonitor patients for signs of cardiac ischemia.
Inform patients of the warning signs and symptoms of hepatotoxicitye.gnauseafatiguelethargypruritusdiarrheajaundiceright upper quadrant tendernessandflu-likesymptomsIf these occurinstruct patients to stop Ponstel and seek immediate medical therapysee WARNINGSHepatotoxicity
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