For ciclosporin, it is recommended that plasma concentrations and clinical condition are closely monitored following initiation or cessation of casodex therapy.
Information about Casodex.
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Read the Patient Information Leaflet if available from your pharmacist before you start taking bicalutamide and each time you get a refillIf you have any questionsask your doctor or pharmacist.
A comprehensive battery of both in vitro and in vivo genotoxicity testsyeast gene conversionAmesEcoliCHO/HGPRThuman lymphocyte cytogeneticmouse micronucleusand rat bone marrow cytogenetic testshas demonstrated that Casodex does not have genotoxic activity.
Other adverse reactionsgreater than or equal to 2but less than 5reported in the Casodex-LHRH analog treatment group are listed below by body system and are in order of decreasing frequency within each body system regardless of causality.
Dose and ScheduleInform patients that therapy with Casodex and the LHRH analog should be started at the same time and that they should not interrupt or stop taking these medications without consulting their healthcare providersee Dosage and Administration2.1
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