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Since the introduction of paxil in the united states, 342 spontaneous cases of deliberate or accidental overdosage during paroxetine treatment have been reported worldwide circa 1999 .

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Postmarketing reportsSyndrome of inappropriate antidiuretic hormone secretionsymptoms suggestive of prolactinemiaRef]

Some young people have thoughts about suicide when first taking an antidepressantYour doctor should check your progress at regular visitsYour family or other caregivers should also be alert to changes in your mood or symptoms.

Potentially life-threatening serotonin syndrome has been reported with SSRIs and SNRIs as monotherapybut particularly with concomitant use of other serotonergic drugs and drugs that impair the metabolism of serotoninSigns and symptoms associated with serotonin syndrome or neuroleptic malignant syndrome included agitationconfusiondiaphoresisdiarrheafeverhypertensionrigidityand tachycardiaand were in some cases associated with concomitant use of serotonergic drugsRef]

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