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Food and drug administration fda has approved flonase allergy relief fluticasone propionate 50 mcg spray , containing the no.

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A drug interaction trial with fluticasone propionate aqueous nasal spray in healthy subjects has shown that ritonavira strong CYP3A4 inhibitorcan significantly increase plasma fluticasone propionate exposureresulting in significantly reduced serum cortisol concentrationssee CLINICAL PHARMACOLOGYDuring postmarketing usethere have been reports of clinically significant drug interactions in patients receiving fluticasone propionate productsincluding FLONASEwith ritonavirresulting in systemic corticosteroid effects including Cushing’s syndrome and adrenal suppression.

Inform patients that glaucoma and cataracts are associated with nasal and inhaled corticosteroid useAdvise patients to notify their healthcare providers if a change in vision is noted while using FLONASE Nasal Spraysee WARNINGS AND PRECAUTIONS

Fluticasone is used to relieve seasonal and year-round allergic and non-allergic nasal symptomssuch as stuffy/runny noseitchingand sneezingIt can also help relieve allergy eye symptoms such as itchywatery eyesThis medication belongs to a class of drugs known as corticosteroidsIt works in your nose to block the effects of substances that cause allergiessuch as pollenpet danderdust mitesmoldand to reduce swelling.

The replacement of a systemic corticosteroid with a topical corticosteroid can be accompanied by signs of adrenal insufficiencyIn additionsome patients may experience symptoms of corticosteroid withdrawale.gjoint and/or muscular painlassitudedepressionPatients previously treated for prolonged periods with systemic corticosteroids and transferred to topical corticosteroids should be carefully monitored for acute adrenal insufficiency in response to stressIn patients who have asthma or other clinical conditions requiring long-term systemic corticosteroid treatmentrapid decreases in systemic corticosteroid dosages may cause a severe exacerbation of their symptoms.

Read the Patient Information that comes with FLONASE Nasal Spray before you start using it and each time you get a refillThere may be new informationThis Patient Information does not take the place of talking to your healthcare provider about your medical condition or treatment.

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