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Postmarketing reportsGlaucomablurred visionmydriasisconjunctival hyperemiahalo visionaccommodation disorderocular irritationcorneal edemaintraocular pressure increasedRef]
Additional adverse reactionsreported in less than two percent of the patients in the Combivent Inhalation Aerosol treatment group include edemafatiguehypertensiondizzinessnervousnessparesthesiatremordysphoniainsomniadiarrheadry mouthdyspepsiavomitingarrhythmiapalpitationtachycardiaarthralgiaanginaincreased sputumtaste perversionand urinary tract infection/dysuria.
Applies to albuterolipratropiuminhalation aerosol liquidinhalation aerosol powderinhalation solutioninhalation spray.
Postmarketing reportsThroat irritationparadoxical bronchospasmnasal congestionpharyngeal edemaRef]
Ipratropium bromide is an anticholinergicparasympatholyticagent whichbased on animal studiesappears to inhibit vagally-mediated reflexes by antagonizing the action of acetylcholinethe transmitter agent released at the neuromuscular junctions in the lungAnticholinergics prevent the increases in intracellular concentration of Cawhich is caused by interaction of acetylcholine with the muscarinic receptors on bronchial smooth muscle.
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