, cimetidine, escitalopram, erythromycin, paroxetine, bupropion, fluoxetine, quinidine, duloxetine, terbinafine, or sertraline can increase clozapine levels and lead to adverse reactions see clinical pharmacology .
Information about Paroxetine.
Take the missed dose as soon as you remember itHoweverif it is almost time for the next doseskip the missed dose and continue your regular dosing scheduleDo not take a double dose to make up for a missed one.
BrisdelleIndicated to treat moderate-to-severe vasomotor symptoms associated with menopause Brisdelle7.5 mg orally at bedtime Paxil CROff-label12.5-25 mg orally once/day.
Concomitant use or within 14 days of MAOIs increases risk of serotonin syndrome Reactions to concomitant administration with MAOIs include tremormyoclonusdiaphoresisnauseavomitingflushingdizzinesshyperthermia with features resembling neuroleptic malignant syndromeseizuresrigidityautonomic instability with possible rapid fluctuations of vital signsand mental status changes that include extreme agitation progressing to delirium and coma Starting paroxetine in a patient who is being treated with linezolid or IV methylene blue is contraindicated because of an increased risk of serotonin syndrome If linezolid or IV methylene blue must be administereddiscontinue SSRI immediately and monitor for CNS toxicitymay resume 24 hr after last linezolid or methylene blue doseor after 2 weeks of monitoring5 weeks for fluoxetinewhichever comes first.
Depression exacerbation ManiarareSerotonin syndrome Suicidal thoughtsrareSuiciderareSeizurerareToxic epidermal necrolysis HyponatremiarareBleedingabnormalrareAcute hepatitisrareStevens-Johnson Syndrome Bone fracture Akathisia.
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clinical experience has shown that therapy with paroxetine is not associated with impairment of cognitive or psychomotor function.
