Hoodia gordonii medicinal herb illustration.
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Many weight loss supplements assert they contain Hoodiabut actual amount or efficacy unverified.
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Obesity is one of the most common health concerns todayHerbal-based food supplements are widely used to treat obesityAmong themthe African cactiform Hoodia gordonii supplements are extremely popularThe development of Hoodia and P57the purported active ingredienthas been problematic due to controversy about intellectual property rights and limited natural resourcesTo datethe true active components and molecular targets of Hoodia remain unclearHerewe demonstrate that Gordonoside Fa compound from Hoodiaactivates GPR119a receptor critically involved in metabolic homeostasisand leads to increased insulin secretion and reduced food intakeThe successful synthesis of Gordonoside F described here will provide an opportunity for developing new drugs in treating metabolic diseases.
But let me tell youit does have side effectsThe most common is a stickydry mouthfollowed by some suspected damage to the liver in the long run and lastlythe risk of seriously depriving the body of energyThese side effects are due to some of its constituentswhich are difficult to remove while processingStillsince hoodia products are herbal and most of its preparations do not contain harmful synthetic chemicals or stimulantsthey are safer than most of the weight loss drugs available in the market that put stress on the heart and metabolism.
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