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Immunosuppessants such as cyclosporine and tacrolimus can produce nephrotoxicity with decreases in creatinine clearance and rises in serum creatinineand because renal excretion is the primary elimination route of fibrate drugs including TRICORthere is a risk that an interaction will lead to deterioration of renal functionThe benefits and risks of using TRICORfenofibrate tabletswith immunosuppressants and other potentially nephrotoxic agents should be carefully consideredand the lowest effective dose employed and renal function monitored.
In rare casesfenofibrate can cause a condition that results in the breakdown of skeletal muscle tissueleading to kidney failureCall your doctor right away if you have unexplained muscle paintendernessor weakness especially if you also have feverunusual tirednessand dark colored urine.
Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficult breathingswelling of your facelipstongueor throat.
Generic NamefenofibrateFEN oh FYE brateBrand NamesAntaraFenoglideLipofenLofibraTriCorTriglideLipidil MicroDom-FenofibrateLipidil SupraLipidil EZ.
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