What health conditions may interact with nimotop nimodipine .
Information about Nimotop.
Read the Patient Information Leaflet if available from your pharmacist before you start taking nimodipine and each time you get a refillIf you have any questionsask your doctor or pharmacist.
Nimodipine is a calcium channel blockerThe contractile processes of smooth muscle cells are dependent upon calcium ionswhich enter these cells during depolarization as slow ionic transmembrane currentsNimodipine inhibits calcium ion transfer into these cells and thus inhibits contractions of vascular smooth muscleIn animal experimentsnimodipine had a greater effect on cerebral arteries than on arteries elsewhere in the body perhaps because it is highly lipophilicallowing it to cross the blood-brain barrierconcentrations of nimodipine as high as 12.5 ng/mL have been detected in the cerebrospinal fluid of nimodipine-treated subarachnoid hemorrhageSAHpatients.
Nimotop tablets should not be administered concomitantly with Nimotop solution.
DO NOT ADMINISTER Nimotop INTRAVENOUSLY OR BY OTHER PARENTERAL ROUTESDEATHS AND SERIOUSLIFE THREATENING ADVERSE EVENTS HAVE OCCURRED WHEN THE CONTENTS OF Nimotop CAPSULES HAVE BEEN INJECTED PARENTERALLYSee WARNINGS and DOSAGE AND ADMINISTRATION
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in addition to the serious side effects listed above, these are the other less serious side effects of nimotop tablets .