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in 3 randomized, placebo-controlled studies of zurampic in combination with a xanthine oxidase inhibitor studies 1 and 2 were with allopurinol and study 3 was with febuxostat for up to 12 months, a total of 511, 510, and 516 patients were treated with zurampic 200 mg, zurampic 400 mg, and placebo, respectively.

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