Debi i am on methotrexate plaquenil for 4 yrs now.
Information about Methotrexate.
This is not a complete list of possible side effectsIf you notice other effects not listed abovecontact your doctor or pharmacist.
Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatmentsIt may also be used to control juvenile rheumatoid arthritisMethotrexate belongs to a class of drugs known as antimetabolitesIt works by slowing or stopping the growth of cancer cells and suppressing the immune system.
Signs of tumor cell breakdownconfusiontirednessnumbness or tinglingmuscle crampsmuscle weaknessvomitingdiarrheafast or slow heart rateseizure.
The good newsThese side effects can often be short-circuited by taking a folic acid supplementFolic acid is the synthetic form of folateOne study found that RA patients on methotrexate who took folic acid supplements lowered the risk of GI problems and mouth sores by 79 percent.
Live vaccinesWhen used with methotrexatelive vaccines raise your risk of infectionThe vaccine may also not work as wellLive vaccinessuch as FluMistare vaccines that contain small amounts of livebut weakenedviruses
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patients in clinical remission are often required to continue methotrexate even if at a lower dose.
