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In larger dosesfludrocortisone acetate inhibits endogenous adrenal cortical secretionthymic activityand pituitary corticotropin excretionpromotes the deposition of liver glycogenandunless protein intake is adequateinduces negative nitrogen balance.

The use of Florinef AcetateFludrocortisone Acetate Tablets USPin patients with active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimenIf corticosteroids are indicated in patients with latent tuberculosis or tuberculin reactivityclose observation is necessary since reactivation of the disease may occurDuring prolonged corticosteroid therapy these patients should receive chemoprophylaxis.

The use of Florinef AcetateFludrocortisone Acetate Tablets USPin patients with active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimenIf corticosteroids are indicated in patients with latent tuberculosis or tuberculin reactivityclose observation is necessary since reactivation of the disease may occurDuring prolonged corticosteroid therapy these patients should receive chemoprophylaxis.

Driving and using machines Fludrocortisone acetate has not been shown to impair your ability to drive or use machinesSteroid Treatment Card Your doctor or pharmacist will have given you a Steroid Treatment Card with your prescription or medicineYOU SHOULD ALWAYS CARRY THIS CARD WITH YOU as it must be shown to any of the following personsDoctor or Nursebefore having any surgery or emergency treatment or if any new treatment is prescribedDentistbefore having any dental surgery Pharmacistbefore buying any medicine Opticianit is advisable to have regular eye tests Fludrocortisone acetate contains lactose Fludrocortisone acetate contains lactoseIf you have been told by your doctor that you have an intolerance to some sugarsyou should discuss this with them before taking this medicine.

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