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Hpain: In a clinical study conductd in halthy subjcts, clopidogl did not ncssitat modiication th hpain dos alt th ct hpain on coagulation. Co-administation hpain had nct on th inhibition platlt agggation inducd by clopidogl. A phamacodynamic intaction btwn clopidogl and hpain is possibl, lading tincasd isk blding. Tho, concomitant us should b undtakn with caution.
Hypsnsitivity tatovastatin, clopidogl any componnt this mdication Activ liv disas, which may includ unxplaind psistnt lvations in hpatic tansaminas lvls Activ pathological blding such as pptic ulc intacanial hmohag Womn wha pgnant may bcom pgnant Lactation.
Oal Anti-coagulants: Th concomitant administation ATOLIP CV with oal anti-coagulants is not commndd sinc it may incas th intnsity blding. Atovastatin had nclinically signiicant ct on pothombin tim whn administd tpatints civing chonic waain tatmnt. Although th administation clopidogl 75 mg p day did not modiy th phamacokintics S-waain (a CYP2C9 substat) Intnational Nomalizd ati(IN) in patints civing long-tm waain thapy, at high concntations in vit, clopidogl inhibits CYP2C9. Co-administation ATOLIP CV with waain incass th isk blding bcaus indpndnt cts clopidogl on hmostasis.
Duc th isk myocadial inaction (MI) duc th isk stok duc th isk vasculaization pocdus and angina.
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